Medical research

The vagaries of laboratory experiments

One usually likes to think that scientists know what they’re doing. Here’s something that might shake your confidence. In bio-medical research, scientists often use cell lines. These are in vitro cells, originally taken from a human or animal donor, which can be experimented on to help develop new drugs or treatments. The problem is that, according to one review, in ‘at least 5 per cent’ of studies, the scientists have totally mixed up where the cells came from. This means that in at least one in 20 studies that were sent off for peer review the scientists were completely confused about the most basic element of their research. They thought,