Bissan Al-Lazikani

The solving of a biological mystery

A representation of a myoglobin protein, found in the muscle tissue of most mammals

DNA is the blueprint that encodes the instructions to make proteins. Proteins are the building blocks and the machines that power life. And proteins make up the tissue that in turn comprise the organs and muscles that make up us. Considering how crucial proteins are to life itself, there is still so much we do not know about them. But Google’s AI firm Deepmind may just have helped us make a giant leap forward.

When a protein is first made inside a living cell, it is merely a chain of connected amino acids — like beads on a string. Yet, it instantaneously folds into unique three-dimensional, beautiful shapes, which enable them to carry out their function. When proteins go wrong — because of mutations or mistakes in folding — serious human diseases emerge, such as cancer and dementia.

Knowing the 3D structures of proteins has a transformative impact on the discovery of new drugs

Knowing the 3D structures of proteins has a transformative impact on the discovery of new drugs.

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