Ever since the Oxford-AstraZeneca team announced the results of its Phase 3 trials last November, there has been a suspicion among some that their vaccine is the poor relation of the messenger RNA vaccines developed by Pfizer and Moderna. It might be cheap compared with the others, it might be easy to store and transport, but the results published last November indicated that it had an efficacy of 70 per cent compared with over 90 per cent for Pfizer and Moderna. Even that was questioned when it was pointed out that the 70 per cent figure was arrived at by mixing different trials, involving different quantities of vaccine. When a half dose was followed by a full dose (a regime which occurred as a result of a mix up of doses) it seemed to have an efficacy rate of 90 per cent, yet when two full doses were given that dropped to 62 per cent.
Ross Clark
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